COMING SOON - H2M Database Online Portal#
We pre-computed
Murine equivalents of over 3,000,000 human variants derived from ClinVar, COSMIC, and AACR-GENIE;
Base editing guide RNAs for over 3,000,000 human-mouse variant pairs;
Prime eiditing guide RNAs for a 5,000 subset of hotspot human mutations and their murine equivalents.
We are going to make it available as an online resource.
PEGG: Prime Editing Guide Generator#
PEGG is a python package that designs prime editing guide RNAs (pegRNAs) and base editing guide RNAs (gRNAs) for use in precision genome editing.
PATTERN#
Pattern is a recharge center that provides support to the greater Broad community. We specialize in design and development projects that create greater scientific understanding and impact.