Index of the interfacial free energy of a folded state(Gs(F))


This index follows the classical definition of the superficial free energy as the product of the surface tension and the area of the species.

Superficial tension is represented with the Kyte-Doolitle hydrophobicity scale (Kyte and Doolitle, 1982). The area values are computed for the corresponding residues in each case.

References

Kyte, J., and Doolitle, R.F., 1982. A Simple Method for Displaying the Hydropathic Character of a Protein. . J. Mol. Biol. 157, 105-132.