Weighted Chain Topology Parameter(wCTP)


The chain topology parameter (CTP) is defined by

Where nr is the number of residues in a protein, nc is the number of inter-residue contacts and DLij is the sequence separation between the contacting residues i and j in the protein sequence (Nolting et al., 2003). The weighted implementation of this index in ProtDCal is as follow:

References

Nolting, B., Schalike, W., Hampel, P., Grundig, F., Gantert, S., Sips, N., Bandlow, W., and Qi, P.X., 2003. Structural determinants of the rate of protein folding. J. Theor. Biol. 223, 299-307.