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1358 items - Showing page 1 of 55
Paper

Incorporation of aspirin modulates the dynamical and phase behavior of the phospholipid membrane

Effect of aspirin on the microscopic dynamics of a membrane has been investigated using quasielastic neutron scattering and neutron spin echo techniques.

Graphical abstract: Incorporation of aspirin modulates the dynamical and phase behavior of the phospholipid membrane
Paper

In situ investigation of supercritical CO2 assisted impregnation of drugs into a polymer by high pressure FTIR micro-spectroscopy

High pressure FTIR micro-spectroscopy to follow the kinetics of the drug loading during the supercritical CO2 assisted impregnation process.

Graphical abstract: In situ investigation of supercritical CO2 assisted impregnation of drugs into a polymer by high pressure FTIR micro-spectroscopy
Paper

Spectroscopic and molecular docking evidence of aspirin and diflunisal binding to DNA: a comparative study

Deciphering the binding mode between aspirin/diflunisal with Ct-DNA.

Graphical abstract: Spectroscopic and molecular docking evidence of aspirin and diflunisal binding to DNA: a comparative study
Paper

Competitive binding of small molecules with biopolymers: a fluorescence spectroscopy and chemometrics study of the interaction of aspirin and ibuprofen with BSA

The competitive interaction of aspirin and ibuprofen with BSA was studied by three-way excitation–emission fluorescence spectra; it showed, with the aid of chemometrics, that the competitive effect of ibuprofen was stronger than that of aspirin.

Graphical abstract: Competitive binding of small molecules with biopolymers: a fluorescence spectroscopy and chemometrics study of the interaction of aspirin and ibuprofen with BSA
Communication

Single crystals of aspirin form II: crystallisation and stability

Crystallisation of aspirin in the presence of aspirin anhydride produces stable crystals of aspirin form II.

Graphical abstract: Single crystals of aspirin form II: crystallisation and stability
Paper

Protective effect of Artemisia campestris extract against aspirin-induced gastric lesions and oxidative stress in rat

The present study aims at evaluating the antiulcer and antioxidant effect of Artemisia campestris aqueous extract (ACAE) as well as the mechanism of action involved in such gastroprotection.

Graphical abstract: Protective effect of Artemisia campestris extract against aspirin-induced gastric lesions and oxidative stress in rat
Paper

Aspirin enhances the osteogenic and anti-inflammatory effects of human mesenchymal stem cells on osteogenic BFP-1 peptide-decorated substrates

The combination of aspirin and an osteogenic BFP-1 peptide-decorated substrate significantly enhances immunomodulation and osteogenic differentiation of hMSCs.

Graphical abstract: Aspirin enhances the osteogenic and anti-inflammatory effects of human mesenchymal stem cells on osteogenic BFP-1 peptide-decorated substrates
Paper

The protective role of Ocimum basilicum L. (Basil) against aspirin-induced gastric ulcer in mice: Impact on oxidative stress, inflammation, motor deficits and anxiety-like behavior

The gastroprotective effect of Ocimum basilicum L. (Basil) hexane extract (OBHE) in aspirin-induced gastric ulcers in mice and its ameliorative effect on behavioral alterations were determined.

Graphical abstract: The protective role of Ocimum basilicum L. (Basil) against aspirin-induced gastric ulcer in mice: Impact on oxidative stress, inflammation, motor deficits and anxiety-like behavior
Paper

Dual-emission ratiometric fluorescence detection of aspirin in human saliva: onsite naked-eye detection and high stability

A highly stable ratiometric fluorescence probe based on dual-emission QDs was designed for the visual detection of aspirin in human saliva.

Graphical abstract: Dual-emission ratiometric fluorescence detection of aspirin in human saliva: onsite naked-eye detection and high stability
Communication

New formulation of old aspirin for better delivery

A hydrophobic, cleavable aspirin analogue was constructed and optimized for its incorporation into delivery vehicles for target-oriented delivery of the widely used anti-inflammatory drug aspirin.

Graphical abstract: New formulation of old aspirin for better delivery
Paper

Natural halloysite nanotubes modified as an aspirin carrier

Natural halloysite nanotubes (HNTs) modified with 3-aminopropyltriethoxysilane were used as an aspirin carrier.

Graphical abstract: Natural halloysite nanotubes modified as an aspirin carrier
Paper

Using a terbium complex as an energy bridge to enhance energy transfer between polyvinyl carbazole and europium complexes

Tb(aspirin)3(phen) is used as an energy bridge to link the route of energy transfer between PVK matrix and europium complex so that both the color purity and luminescent efficiency of the Eu3+ are improved.

Graphical abstract: Using a terbium complex as an energy bridge to enhance energy transfer between polyvinyl carbazole and europium complexes
Paper

The dissolution and diffusion of aspirin in aqueous media

Paper

Characterization of polymer micelles with hemocompatibility based on N-succinyl-chitosan grafting with long chain hydrophobic groups and loading aspirin

To enhance the self-aggregation of N-succinyl-chitosan (SCCS), 2-hydroxy-3-(octadecyloxy)propyl groups were employed as hydrophobic groups to modify SCCS to synthesise amphiphilic chitosan derivatives.

Graphical abstract: Characterization of polymer micelles with hemocompatibility based on N-succinyl-chitosan grafting with long chain hydrophobic groups and loading aspirin
Paper

Efficacy of variable dosage of aspirin in combating methotrexate-induced intestinal toxicity

The aim of the present study was to study in detail the effect of variable doses of aspirin on intestinal toxicity.

Graphical abstract: Efficacy of variable dosage of aspirin in combating methotrexate-induced intestinal toxicity
Paper

Asplatin enhances drug efficacy by altering the cellular response

Asplatin, the conjugate of aspirin and cisplatin, promotes cell apoptosis by highly efficient activation of the BCL-2 associated mitochondrial pathway.

Graphical abstract: Asplatin enhances drug efficacy by altering the cellular response
Paper

The hydrolysis of aspirin. A determination of the thermodynamic dissociation constant and a study of the reaction kinetics by ultra-violet spectrophotometry

Paper

On the glassy and supercooled liquid states of a common medicament: Aspirin

Open Access Paper

HPLC/PDA/ESI-MS/MS analysis of chamomile decoction and mechanism of its protective effects on aspirin-induced small bowel injuries

The aim of the present study is to evaluate the effect of chamomile (Matricaria recutita L.) decoction extract (CDE) on aspirin-induced small bowel injuries.

Graphical abstract: HPLC/PDA/ESI-MS/MS analysis of chamomile decoction and mechanism of its protective effects on aspirin-induced small bowel injuries
Open Access Paper

Multiscale modeling of aspirin dissolution: from molecular resolution to experimental scales of time and size

Predicted absolute and face-specific rate constants of aspirin dissolution are incorporated in a simulation based on the equations of classical mass transfer to reproduce kinetic dissolution in experiment using a Jamin-type interferometer.

Graphical abstract: Multiscale modeling of aspirin dissolution: from molecular resolution to experimental scales of time and size
Paper

Real-time monitoring of powder mixing in a convective blender using non-invasive reflectance NIR spectrometry

Non-invasive NIR spectrometry can be used to monitor in real time the dynamics of powder mixing, determine compositional information and monitor possible changes in particle size during blending.

Graphical abstract: Real-time monitoring of powder mixing in a convective blender using non-invasive reflectance NIR spectrometry
Open Access Paper

EPR studies of intermolecular interactions and competitive binding of drugs in a drug–BSA binding model

EPR spectroscopy is a very promising technique to understand the details of drug binding and competitive drug binding to proteins.

Graphical abstract: EPR studies of intermolecular interactions and competitive binding of drugs in a drug–BSA binding model
Paper

Graphene quantum dot-decorated mesoporous silica nanoparticles for high aspirin loading capacity and its pH-triggered release

In this paper, fluorescent graphene quantum dots (GQDs) grafted onto the surface of mesoporous silica nanoparticle (MSN) vehicles were prepared and characterized.

Graphical abstract: Graphene quantum dot-decorated mesoporous silica nanoparticles for high aspirin loading capacity and its pH-triggered release
Paper

Fabrication of mesoporous silica nanospheres with radially oriented mesochannels by microemulsion templating for adsorption and controlled release of aspirin

The MSN spheres with narrow size distribution and radially oriented mesoporous channels were prepared using an O/W microemulsion system, consisting of CTAB (or PVP), ethanol, cyclohexane and water as template.

Graphical abstract: Fabrication of mesoporous silica nanospheres with radially oriented mesochannels by microemulsion templating for adsorption and controlled release of aspirin
Paper

Novel 7-(dimethylamino)fluorene-based fluorescent probes and their binding to human serum albumin

Compounds 1 and 2 are highly sensitive fluorescent probes which bind to sites I and II, respectively, of human serum albumin.

Graphical abstract: Novel 7-(dimethylamino)fluorene-based fluorescent probes and their binding to human serum albumin
1358 items - Showing page 1 of 55

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