{% extends "base.html" %} {% block head %} {{ super() }} {% endblock %} {% block title %}{{ graph }}{% endblock %} {% block content %}
{% if graph.description %} {{ graph.description }} {% else %} Provenance information is extracted from the header in the source BEL document. {% endif %}
Each node in a BEL graph is assigned a type. Most nodes are then identified with a namespace:identifier pair, or a definition based on other nodes as in the case of complexes, composites, and chemical reactions.
Reference | BEL |
---|---|
{{ 'pmid' if d['citation']['type'] =='PubMed' else d['citation']['type'] }}:{{ d['citation']['reference'] }} | {{ graph.edge_to_bel(u, v, d) }} |
These pairs of nodes represent motifs like A increases B
and
B decreases A
.
Node A | Node B |
---|---|
{{ source }} | {{ target }} |
These pairs of nodes have a contradiction in their causal relationships, meaning they
have more than one of INCREASES
, DECREASES
, or CAUSES NO
CHANGE
. This may be due to different experimental conditions, so these statements
need to be carefully considered in analyses.
Source | Relations | Target |
---|---|---|
{{ source }} | {{ ', '.join(relations) }} | {{ target }} |
A increases
B
and B increases A
.
A decreases
B
and B decreases A
.
While neither chaotic nor dampened pairs are biologically invalid, they require additional context to understand their regulation.
Type | Node A | Node B |
---|---|---|
{{ label }} | {{ source }} | {{ target }} |
Analysis of triple stability comes from a deep graph theoretic background. It identifies triangles within the graph that have logically inconsistent relations.
A positiveCorrelation B
, B negativeCorrelation
C
, but C positiveCorrelation A
.
A negativeCorrelation B
, B negativeCorrelation
C
, and C negativeCorrelation A
.
A increases B
, A decreases C
, and C
positiveCorrelation A
.
A increases B
, A increases C
, and C
negativeCorrelation A
.
A decreases B
, A decreases C
, and C
negativeCorrelation A
.
Type | Node A | Node B | Node C |
---|---|---|---|
{{ label }} | {{ a }} | {{ b }} | {{ c }} |
Like unstable pairs, unstable triplets require additional context to understand their mechanisms of regulation.
A
increases B
, B increases C
, and C increases A
.
A
decreases B
, B decreases C
, and C decreases A
.
Type | Node A | Node B | Node C |
---|---|---|---|
{{ label }} | {{ a }} | {{ b }} | {{ c }} |
Pathologies are more dogmatically the result of molecular and physical processes, and do not necessarily make sense as the subject of causal statements.
Source | Relation | Target |
---|---|---|
{{ source }} | {{ relation }} | {{ target }} |