E.coli core DFBA model

Model version: 1

UPDATE submodel

Submodel for dynamically updating the metabolite count. This updates the ode model based on the FBA fluxes.

Description

This is a metabolism model of Homo sapiens in SBML format.

The content of this model has been carefully created in a manual research effort. This file has been exported from the software COBRApy and further processed with the JSBML-based ModelPolisher application.

This file has been produced by the Systems Biology Research Group using BiGG Models knowledge-base version of Nov 21, 2016, where it is currently hosted and identified by: iAB_RBC_283.

Terms of use

Redistribution and use of any part of this model from BiGG Models knowledge-base, with or without modification, are permitted provided that the following conditions are met:

Redistributions of this SBML file must retain the above copyright notice, this list of conditions and the following disclaimer.
Redistributions in a different form must reproduce the above copyright notice, this list of conditions and the following disclaimer in the documentation and/or other materials provided with the distribution.

This model is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.

For specific licensing terms about this particular model and regulations of commercial use, see this model in BiGG Models knowledge-base.

References

When using content from BiGG Models knowledge-base in your research works, please cite

King ZA, Lu JS, Dräger A, Miller PC, Federowicz S, Lerman JA, Ebrahim A, Palsson BO, and Lewis NE. (2015).: BiGG Models: A platform for integrating, standardizing, and sharing genome-scale models. Nucl Acids Res. doi:10.1093/nar/gkv1049

Model : rbc_update

Creator
Matthias, Koenig, Humboldt University Berlin, konigmatt@googlemail.com
Created: 2017-03-31 17:30
Modified: 2017-03-31 17:30

SBO:0000293

id	rbc_update
name	rbc (UPDATE)
version	L3V1
time	h
substance	mmol
extent	mmol
volume	l
area	m2
length	m

type	UnitDefinitions [12]	units
UnitDefinition	h	$3600 s$
UnitDefinition	g	$g$
UnitDefinition	m	$m$
UnitDefinition	m2	$m 2$
UnitDefinition	l	$litre$
UnitDefinition	mmol	$103 mole$
UnitDefinition	per_h	$1 3600 s$
UnitDefinition	mmol_per_h	$103 mole 3600 s$
UnitDefinition	mmol_per_l	$103 mole litre$
UnitDefinition	l_per_mmol	$litre 103 mole$
UnitDefinition	g_per_l	$g litre$
UnitDefinition	g_per_mmol	$g 103 mole$

type	Compartments [1]	name	size	constant	spatial dimensions	unit	derived unit	sbo	cvterm
Compartment	blood	blood	1.0	T	3	l	$litre$

type	Species [76]	name	compartment	boundary condition	constant	initial concentration	substance units	derived units
Species	ins_e	Inosine	blood	F	F	1.0	mmol	$103 mole litre$
Species	gln__L_e	L-Glutamine	blood	F	F	1.0	mmol	$103 mole litre$
Species	lnlc_e	Lnlc c	blood	F	F	1.0	mmol	$103 mole litre$
Species	thm_e	Thiamin	blood	F	F	1.0	mmol	$103 mole litre$
Species	ncam_e	Nicotinamide	blood	F	F	1.0	mmol	$103 mole litre$
Species	nac_e	Nicotinate	blood	F	F	1.0	mmol	$103 mole litre$
Species	urea_e	Urea	blood	F	F	1.0	mmol	$103 mole litre$
Species	hco3_e	Bicarbonate	blood	F	F	1.0	mmol	$103 mole litre$
Species	fum_e	Fumarate	blood	F	F	1.0	mmol	$103 mole litre$
Species	pydxn_e	Pyridoxine	blood	F	F	1.0	mmol	$103 mole litre$
Species	M_4pyrdx_e	4pyrdx c	blood	F	F	1.0	mmol	$103 mole litre$
Species	normete__L_e	Normete L c	blood	F	F	1.0	mmol	$103 mole litre$
Species	bilglcur_e	Bilglcur c	blood	F	F	1.0	mmol	$103 mole litre$
Species	glyc_e	Glycerol	blood	F	F	1.0	mmol	$103 mole litre$
Species	h2o_e	H2O	blood	F	F	1.0	mmol	$103 mole litre$
Species	h_e	H+	blood	F	F	1.0	mmol	$103 mole litre$
Species	lac__L_e	L-Lactate	blood	F	F	1.0	mmol	$103 mole litre$
Species	sprm_e	Spermine C10H30N4	blood	F	F	1.0	mmol	$103 mole litre$
Species	M_3moxtyr_e	3moxtyr c	blood	F	F	1.0	mmol	$103 mole litre$
Species	nrpphr_e	Nrpphr c	blood	F	F	1.0	mmol	$103 mole litre$
Species	acnam_e	N-Acetylneuraminate	blood	F	F	1.0	mmol	$103 mole litre$
Species	thmmp_e	Thiamin monophosphate	blood	F	F	1.0	mmol	$103 mole litre$
Species	co2_e	CO2	blood	F	F	1.0	mmol	$103 mole litre$
Species	lac__D_e	D-Lactate	blood	F	F	1.0	mmol	$103 mole litre$
Species	mal__L_e	L-Malate	blood	F	F	1.0	mmol	$103 mole litre$
Species	ocdcea_e	Octadecenoate (n-C18:1)	blood	F	F	1.0	mmol	$103 mole litre$
Species	k_e	Potassium	blood	F	F	1.0	mmol	$103 mole litre$
Species	na1_e	Sodium	blood	F	F	1.0	mmol	$103 mole litre$
Species	dhdascb_e	Dhdascb c	blood	F	F	1.0	mmol	$103 mole litre$
Species	cl_e	Chloride	blood	F	F	1.0	mmol	$103 mole litre$
Species	arg__L_e	L-Arginine	blood	F	F	1.0	mmol	$103 mole litre$
Species	nh4_e	Ammonium	blood	F	F	1.0	mmol	$103 mole litre$
Species	adrnl_e	Adrnl c	blood	F	F	1.0	mmol	$103 mole litre$
Species	ala__L_e	L-Alanine	blood	F	F	1.0	mmol	$103 mole litre$
Species	ptrc_e	Putrescine	blood	F	F	1.0	mmol	$103 mole litre$
Species	gal_e	D-Galactose	blood	F	F	1.0	mmol	$103 mole litre$
Species	ascb__L_e	L-Ascorbate	blood	F	F	1.0	mmol	$103 mole litre$
Species	h2o2_e	Hydrogen peroxide	blood	F	F	1.0	mmol	$103 mole litre$
Species	mepi_e	Mepi c	blood	F	F	1.0	mmol	$103 mole litre$
Species	acald_e	Acetaldehyde	blood	F	F	1.0	mmol	$103 mole litre$
Species	leuktrB4_e	LeuktrB4 c	blood	F	F	1.0	mmol	$103 mole litre$
Species	adn_e	Adenosine	blood	F	F	1.0	mmol	$103 mole litre$
Species	pi_e	Phosphate	blood	F	F	1.0	mmol	$103 mole litre$
Species	orot_e	Orotate	blood	F	F	1.0	mmol	$103 mole litre$
Species	M_5aop_e	5-Amino-4-oxopentanoate	blood	F	F	1.0	mmol	$103 mole litre$
Species	phe__L_e	L-Phenylalanine	blood	F	F	1.0	mmol	$103 mole litre$
Species	etha_e	Ethanolamine	blood	F	F	1.0	mmol	$103 mole litre$
Species	co_e	Carbon monoxide	blood	F	F	1.0	mmol	$103 mole litre$
Species	dopa_e	Dopamine	blood	F	F	1.0	mmol	$103 mole litre$
Species	man_e	D-Mannose	blood	F	F	1.0	mmol	$103 mole litre$
Species	gam_e	D-Glucosamine	blood	F	F	1.0	mmol	$103 mole litre$
Species	pydx_e	Pyridoxal	blood	F	F	1.0	mmol	$103 mole litre$
Species	ac_e	Acetate	blood	F	F	1.0	mmol	$103 mole litre$
Species	hxan_e	Hypoxanthine	blood	F	F	1.0	mmol	$103 mole litre$
Species	glc__D_e	D-Glucose	blood	F	F	1.0	mmol	$103 mole litre$
Species	uri_e	Uridine	blood	F	F	1.0	mmol	$103 mole litre$
Species	ade_e	Adenine	blood	F	F	1.0	mmol	$103 mole litre$
Species	camp_e	CAMP	blood	F	F	1.0	mmol	$103 mole litre$
Species	hcys__L_e	L-Homocysteine	blood	F	F	1.0	mmol	$103 mole litre$
Species	o2_e	O2	blood	F	F	1.0	mmol	$103 mole litre$
Species	hdca_e	Hexadecanoate (n-C16:0)	blood	F	F	1.0	mmol	$103 mole litre$
Species	pydam_e	Pyridoxamine	blood	F	F	1.0	mmol	$103 mole litre$
Species	M_35cgmp_e	3',5'-Cyclic GMP	blood	F	F	1.0	mmol	$103 mole litre$
Species	met__L_e	L-Methionine	blood	F	F	1.0	mmol	$103 mole litre$
Species	gly_e	Glycine	blood	F	F	1.0	mmol	$103 mole litre$
Species	cys__L_e	L-Cysteine	blood	F	F	1.0	mmol	$103 mole litre$
Species	chol_e	Choline	blood	F	F	1.0	mmol	$103 mole litre$
Species	ca2_e	Calcium	blood	F	F	1.0	mmol	$103 mole litre$
Species	gluala_e	5 L Glutamyl L alanine C8H13N2O5	blood	F	F	1.0	mmol	$103 mole litre$
Species	ribflv_e	Riboflavin	blood	F	F	1.0	mmol	$103 mole litre$
Species	fru_e	D-Fructose	blood	F	F	1.0	mmol	$103 mole litre$
Species	spmd_e	Spermidine	blood	F	F	1.0	mmol	$103 mole litre$
Species	fe2_e	Fe2+	blood	F	F	1.0	mmol	$103 mole litre$
Species	leuktrA4_e	LeuktrA4 c	blood	F	F	1.0	mmol	$103 mole litre$
Species	pyr_e	Pyruvate	blood	F	F	1.0	mmol	$103 mole litre$
Species	gthox_e	Oxidized glutathione	blood	F	F	1.0	mmol	$103 mole litre$

type	Parameters [76]	value	unit	derived unit	constant	sbo
Parameter	EX_ins_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_gln__L_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_lnlc_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_thm_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_ncam_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_nac_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_urea_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_hco3_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_fum_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_pydxn_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_M_4pyrdx_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_normete__L_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_bilglcur_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_glyc_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_h2o_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_h_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_lac__L_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_sprm_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_M_3moxtyr_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_nrpphr_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_acnam_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_thmmp_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_co2_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_lac__D_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_mal__L_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_ocdcea_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_k_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_na1_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_dhdascb_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_cl_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_arg__L_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_nh4_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_adrnl_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_ala__L_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_ptrc_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_gal_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_ascb__L_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_h2o2_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_mepi_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_acald_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_leuktrB4_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_adn_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_pi_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_orot_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_M_5aop_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_phe__L_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_etha_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_co_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_dopa_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_man_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_gam_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_pydx_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_ac_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_hxan_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_glc__D_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_uri_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_ade_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_camp_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_hcys__L_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_o2_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_hdca_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_pydam_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_M_35cgmp_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_met__L_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_gly_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_cys__L_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_chol_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_ca2_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_gluala_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_ribflv_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_fru_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_spmd_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_fe2_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_leuktrA4_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_pyr_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613
Parameter	EX_gthox_e	1.0	mmol_per_h	$103 mole 3600 s$	T	SBO:0000613

type	Reactions [76]		equation	formula	derived units
Reaction	update_ins_e	⇆	ins_e ⇆	$EX_ins_e$	$103 mole 3600 s$
Reaction	update_gln__L_e	⇆	gln__L_e ⇆	$EX_gln__L_e$	$103 mole 3600 s$
Reaction	update_lnlc_e	⇆	lnlc_e ⇆	$EX_lnlc_e$	$103 mole 3600 s$
Reaction	update_thm_e	⇆	thm_e ⇆	$EX_thm_e$	$103 mole 3600 s$
Reaction	update_ncam_e	⇆	ncam_e ⇆	$EX_ncam_e$	$103 mole 3600 s$
Reaction	update_nac_e	⇆	nac_e ⇆	$EX_nac_e$	$103 mole 3600 s$
Reaction	update_urea_e	⇆	urea_e ⇆	$EX_urea_e$	$103 mole 3600 s$
Reaction	update_hco3_e	⇆	hco3_e ⇆	$EX_hco3_e$	$103 mole 3600 s$
Reaction	update_fum_e	⇆	fum_e ⇆	$EX_fum_e$	$103 mole 3600 s$
Reaction	update_pydxn_e	⇆	pydxn_e ⇆	$EX_pydxn_e$	$103 mole 3600 s$
Reaction	update_M_4pyrdx_e	⇆	M_4pyrdx_e ⇆	$EX_M_4pyrdx_e$	$103 mole 3600 s$
Reaction	update_normete__L_e	⇆	normete__L_e ⇆	$EX_normete__L_e$	$103 mole 3600 s$
Reaction	update_bilglcur_e	⇆	bilglcur_e ⇆	$EX_bilglcur_e$	$103 mole 3600 s$
Reaction	update_glyc_e	⇆	glyc_e ⇆	$EX_glyc_e$	$103 mole 3600 s$
Reaction	update_h2o_e	⇆	h2o_e ⇆	$EX_h2o_e$	$103 mole 3600 s$
Reaction	update_h_e	⇆	h_e ⇆	$EX_h_e$	$103 mole 3600 s$
Reaction	update_lac__L_e	⇆	lac__L_e ⇆	$EX_lac__L_e$	$103 mole 3600 s$
Reaction	update_sprm_e	⇆	sprm_e ⇆	$EX_sprm_e$	$103 mole 3600 s$
Reaction	update_M_3moxtyr_e	⇆	M_3moxtyr_e ⇆	$EX_M_3moxtyr_e$	$103 mole 3600 s$
Reaction	update_nrpphr_e	⇆	nrpphr_e ⇆	$EX_nrpphr_e$	$103 mole 3600 s$
Reaction	update_acnam_e	⇆	acnam_e ⇆	$EX_acnam_e$	$103 mole 3600 s$
Reaction	update_thmmp_e	⇆	thmmp_e ⇆	$EX_thmmp_e$	$103 mole 3600 s$
Reaction	update_co2_e	⇆	co2_e ⇆	$EX_co2_e$	$103 mole 3600 s$
Reaction	update_lac__D_e	⇆	lac__D_e ⇆	$EX_lac__D_e$	$103 mole 3600 s$
Reaction	update_mal__L_e	⇆	mal__L_e ⇆	$EX_mal__L_e$	$103 mole 3600 s$
Reaction	update_ocdcea_e	⇆	ocdcea_e ⇆	$EX_ocdcea_e$	$103 mole 3600 s$
Reaction	update_k_e	⇆	k_e ⇆	$EX_k_e$	$103 mole 3600 s$
Reaction	update_na1_e	⇆	na1_e ⇆	$EX_na1_e$	$103 mole 3600 s$
Reaction	update_dhdascb_e	⇆	dhdascb_e ⇆	$EX_dhdascb_e$	$103 mole 3600 s$
Reaction	update_cl_e	⇆	cl_e ⇆	$EX_cl_e$	$103 mole 3600 s$
Reaction	update_arg__L_e	⇆	arg__L_e ⇆	$EX_arg__L_e$	$103 mole 3600 s$
Reaction	update_nh4_e	⇆	nh4_e ⇆	$EX_nh4_e$	$103 mole 3600 s$
Reaction	update_adrnl_e	⇆	adrnl_e ⇆	$EX_adrnl_e$	$103 mole 3600 s$
Reaction	update_ala__L_e	⇆	ala__L_e ⇆	$EX_ala__L_e$	$103 mole 3600 s$
Reaction	update_ptrc_e	⇆	ptrc_e ⇆	$EX_ptrc_e$	$103 mole 3600 s$
Reaction	update_gal_e	⇆	gal_e ⇆	$EX_gal_e$	$103 mole 3600 s$
Reaction	update_ascb__L_e	⇆	ascb__L_e ⇆	$EX_ascb__L_e$	$103 mole 3600 s$
Reaction	update_h2o2_e	⇆	h2o2_e ⇆	$EX_h2o2_e$	$103 mole 3600 s$
Reaction	update_mepi_e	⇆	mepi_e ⇆	$EX_mepi_e$	$103 mole 3600 s$
Reaction	update_acald_e	⇆	acald_e ⇆	$EX_acald_e$	$103 mole 3600 s$
Reaction	update_leuktrB4_e	⇆	leuktrB4_e ⇆	$EX_leuktrB4_e$	$103 mole 3600 s$
Reaction	update_adn_e	⇆	adn_e ⇆	$EX_adn_e$	$103 mole 3600 s$
Reaction	update_pi_e	⇆	pi_e ⇆	$EX_pi_e$	$103 mole 3600 s$
Reaction	update_orot_e	⇆	orot_e ⇆	$EX_orot_e$	$103 mole 3600 s$
Reaction	update_M_5aop_e	⇆	M_5aop_e ⇆	$EX_M_5aop_e$	$103 mole 3600 s$
Reaction	update_phe__L_e	⇆	phe__L_e ⇆	$EX_phe__L_e$	$103 mole 3600 s$
Reaction	update_etha_e	⇆	etha_e ⇆	$EX_etha_e$	$103 mole 3600 s$
Reaction	update_co_e	⇆	co_e ⇆	$EX_co_e$	$103 mole 3600 s$
Reaction	update_dopa_e	⇆	dopa_e ⇆	$EX_dopa_e$	$103 mole 3600 s$
Reaction	update_man_e	⇆	man_e ⇆	$EX_man_e$	$103 mole 3600 s$
Reaction	update_gam_e	⇆	gam_e ⇆	$EX_gam_e$	$103 mole 3600 s$
Reaction	update_pydx_e	⇆	pydx_e ⇆	$EX_pydx_e$	$103 mole 3600 s$
Reaction	update_ac_e	⇆	ac_e ⇆	$EX_ac_e$	$103 mole 3600 s$
Reaction	update_hxan_e	⇆	hxan_e ⇆	$EX_hxan_e$	$103 mole 3600 s$
Reaction	update_glc__D_e	⇆	glc__D_e ⇆	$EX_glc__D_e$	$103 mole 3600 s$
Reaction	update_uri_e	⇆	uri_e ⇆	$EX_uri_e$	$103 mole 3600 s$
Reaction	update_ade_e	⇆	ade_e ⇆	$EX_ade_e$	$103 mole 3600 s$
Reaction	update_camp_e	⇆	camp_e ⇆	$EX_camp_e$	$103 mole 3600 s$
Reaction	update_hcys__L_e	⇆	hcys__L_e ⇆	$EX_hcys__L_e$	$103 mole 3600 s$
Reaction	update_o2_e	⇆	o2_e ⇆	$EX_o2_e$	$103 mole 3600 s$
Reaction	update_hdca_e	⇆	hdca_e ⇆	$EX_hdca_e$	$103 mole 3600 s$
Reaction	update_pydam_e	⇆	pydam_e ⇆	$EX_pydam_e$	$103 mole 3600 s$
Reaction	update_M_35cgmp_e	⇆	M_35cgmp_e ⇆	$EX_M_35cgmp_e$	$103 mole 3600 s$
Reaction	update_met__L_e	⇆	met__L_e ⇆	$EX_met__L_e$	$103 mole 3600 s$
Reaction	update_gly_e	⇆	gly_e ⇆	$EX_gly_e$	$103 mole 3600 s$
Reaction	update_cys__L_e	⇆	cys__L_e ⇆	$EX_cys__L_e$	$103 mole 3600 s$
Reaction	update_chol_e	⇆	chol_e ⇆	$EX_chol_e$	$103 mole 3600 s$
Reaction	update_ca2_e	⇆	ca2_e ⇆	$EX_ca2_e$	$103 mole 3600 s$
Reaction	update_gluala_e	⇆	gluala_e ⇆	$EX_gluala_e$	$103 mole 3600 s$
Reaction	update_ribflv_e	⇆	ribflv_e ⇆	$EX_ribflv_e$	$103 mole 3600 s$
Reaction	update_fru_e	⇆	fru_e ⇆	$EX_fru_e$	$103 mole 3600 s$
Reaction	update_spmd_e	⇆	spmd_e ⇆	$EX_spmd_e$	$103 mole 3600 s$
Reaction	update_fe2_e	⇆	fe2_e ⇆	$EX_fe2_e$	$103 mole 3600 s$
Reaction	update_leuktrA4_e	⇆	leuktrA4_e ⇆	$EX_leuktrA4_e$	$103 mole 3600 s$
Reaction	update_pyr_e	⇆	pyr_e ⇆	$EX_pyr_e$	$103 mole 3600 s$
Reaction	update_gthox_e	⇆	gthox_e ⇆	$EX_gthox_e$	$103 mole 3600 s$