e_coli_core - [organism]


E.coli core DFBA model

Model version: 4

DFBA FBA submodel.

Description

This is a metabolism model of Escherichia coli str. K-12 substr. MG1655 in SBML format.

The content of this model has been carefully created in a manual research effort. This file has been exported from the software COBRApy and further processed with the JSBML-based ModelPolisher application.
This file has been produced by the Systems Biology Research Group using BiGG Models knowledge-base version of Nov 21, 2016, where it is currently hosted and identified by: e_coli_core.

Terms of use

Copyright © 2016 The Regents of the University of California.

Redistribution and use of any part of this model from BiGG Models knowledge-base, with or without modification, are permitted provided that the following conditions are met:

  1. Redistributions of this SBML file must retain the above copyright notice, this list of conditions and the following disclaimer.
  2. Redistributions in a different form must reproduce the above copyright notice, this list of conditions and the following disclaimer in the documentation and/or other materials provided with the distribution.
This model is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.

For specific licensing terms about this particular model and regulations of commercial use, see this model in BiGG Models knowledge-base.

References

When using content from BiGG Models knowledge-base in your research works, please cite
King ZA, Lu JS, Dräger A, Miller PC, Federowicz S, Lerman JA, Ebrahim A, Palsson BO, and Lewis NE. (2015).
BiGG Models: A platform for integrating, standardizing, and sharing genome-scale models. Nucl Acids Res. doi:10.1093/nar/gkv1049

Model : ecoli_fba

SBML model


SBO:0000624
BQB_HAS_TAXON
511145
BQM_IS
e_coli_core
BQM_IS_DESCRIBED_BY
ecosalplus.10.2.1
idecoli_fba
nameecoli (FBA)
versionL3V1
timeh
substancemmol
extentmmol
volumel
aream2
lengthm
UnitDefinitions [13] name units sbo cvterm
mmol_per_gDW_per_hr 10 3 mole g 3600 s
h 3600 s
g g
m m
m2 m 2
l litre
mmol 10 3 mole
per_h 1 3600 s
mmol_per_h 10 3 mole 3600 s
mmol_per_l 10 3 mole litre
l_per_mmol litre 10 3 mole
g_per_l g litre
g_per_mmol g 10 3 mole

Compartments [2] name size constant spatial dimensions unit derived unit sbo cvterm
c cytosol 0 l litre
BQB_IS
c
e extracellular space 0 l litre
BQB_IS
e

Species [72] name compartment boundary condition constant initial amount initial concentration substance units derived units sbo cvterm
M_13dpg_c 3-Phospho-D-glyceroyl phosphate
C3H4O10P2
c 0.0 mmol 10 3 mole litre
M_2pg_c D-Glycerate 2-phosphate
C3H4O7P
c 0.0 mmol 10 3 mole litre
M_3pg_c 3-Phospho-D-glycerate
C3H4O7P
c 0.0 mmol 10 3 mole litre
M_6pgc_c 6-Phospho-D-gluconate
C6H10O10P
c 0.0 mmol 10 3 mole litre
M_6pgl_c 6-phospho-D-glucono-1,5-lactone
C6H9O9P
c 0.0 mmol 10 3 mole litre
ac_c Acetate
C2H3O2
c 0.0 mmol 10 3 mole litre
ac_e Acetate
C2H3O2
e 0.0 mmol 10 3 mole litre
acald_c Acetaldehyde
C2H4O
c 0.0 mmol 10 3 mole litre
acald_e Acetaldehyde
C2H4O
e 0.0 mmol 10 3 mole litre
accoa_c Acetyl-CoA
C23H34N7O17P3S
c 0.0 mmol 10 3 mole litre
acon_C_c Cis-Aconitate
C6H3O6
c 0.0 mmol 10 3 mole litre
actp_c Acetyl phosphate
C2H3O5P
c 0.0 mmol 10 3 mole litre
adp_c ADP
C10H12N5O10P2
c 0.0 mmol 10 3 mole litre
akg_c 2-Oxoglutarate
C5H4O5
c 0.0 mmol 10 3 mole litre
akg_e 2-Oxoglutarate
C5H4O5
e 0.0 mmol 10 3 mole litre
amp_c AMP
C10H12N5O7P
c 0.0 mmol 10 3 mole litre
atp_c ATP
C10H12N5O13P3
c 0.0 mmol 10 3 mole litre
cit_c Citrate
C6H5O7
c 0.0 mmol 10 3 mole litre
co2_c CO2
CO2
c 0.0 mmol 10 3 mole litre
co2_e CO2
CO2
e 0.0 mmol 10 3 mole litre
coa_c Coenzyme A
C21H32N7O16P3S
c 0.0 mmol 10 3 mole litre
dhap_c Dihydroxyacetone phosphate
C3H5O6P
c 0.0 mmol 10 3 mole litre
e4p_c D-Erythrose 4-phosphate
C4H7O7P
c 0.0 mmol 10 3 mole litre
etoh_c Ethanol
C2H6O
c 0.0 mmol 10 3 mole litre
etoh_e Ethanol
C2H6O
e 0.0 mmol 10 3 mole litre
f6p_c D-Fructose 6-phosphate
C6H11O9P
c 0.0 mmol 10 3 mole litre
fdp_c D-Fructose 1,6-bisphosphate
C6H10O12P2
c 0.0 mmol 10 3 mole litre
for_c Formate
CH1O2
c 0.0 mmol 10 3 mole litre
for_e Formate
CH1O2
e 0.0 mmol 10 3 mole litre
fru_e D-Fructose
C6H12O6
e 0.0 mmol 10 3 mole litre
fum_c Fumarate
C4H2O4
c 0.0 mmol 10 3 mole litre
fum_e Fumarate
C4H2O4
e 0.0 mmol 10 3 mole litre
g3p_c Glyceraldehyde 3-phosphate
C3H5O6P
c 0.0 mmol 10 3 mole litre
g6p_c D-Glucose 6-phosphate
C6H11O9P
c 0.0 mmol 10 3 mole litre
glc__D_e D-Glucose
C6H12O6
e 0.0 mmol 10 3 mole litre
gln__L_c L-Glutamine
C5H10N2O3
c 0.0 mmol 10 3 mole litre
gln__L_e L-Glutamine
C5H10N2O3
e 0.0 mmol 10 3 mole litre
glu__L_c L-Glutamate
C5H8NO4
c 0.0 mmol 10 3 mole litre
glu__L_e L-Glutamate
C5H8NO4
e 0.0 mmol 10 3 mole litre
glx_c Glyoxylate
C2H1O3
c 0.0 mmol 10 3 mole litre
h2o_c H2O
H2O
c 0.0 mmol 10 3 mole litre
h2o_e H2O
H2O
e 0.0 mmol 10 3 mole litre
h_c H+
H
c 0.0 mmol 10 3 mole litre
h_e H+
H
e 0.0 mmol 10 3 mole litre
icit_c Isocitrate
C6H5O7
c 0.0 mmol 10 3 mole litre
lac__D_c D-Lactate
C3H5O3
c 0.0 mmol 10 3 mole litre
lac__D_e D-Lactate
C3H5O3
e 0.0 mmol 10 3 mole litre
mal__L_c L-Malate
C4H4O5
c 0.0 mmol 10 3 mole litre
mal__L_e L-Malate
C4H4O5
e 0.0 mmol 10 3 mole litre
nad_c Nicotinamide adenine dinucleotide
C21H26N7O14P2
c 0.0 mmol 10 3 mole litre
nadh_c Nicotinamide adenine dinucleotide - reduced
C21H27N7O14P2
c 0.0 mmol 10 3 mole litre
nadp_c Nicotinamide adenine dinucleotide phosphate
C21H25N7O17P3
c 0.0 mmol 10 3 mole litre
nadph_c Nicotinamide adenine dinucleotide phosphate - reduced
C21H26N7O17P3
c 0.0 mmol 10 3 mole litre
nh4_c Ammonium
H4N
c 0.0 mmol 10 3 mole litre
nh4_e Ammonium
H4N
e 0.0 mmol 10 3 mole litre
o2_c O2
O2
c 0.0 mmol 10 3 mole litre
o2_e O2
O2
e 0.0 mmol 10 3 mole litre
oaa_c Oxaloacetate
C4H2O5
c 0.0 mmol 10 3 mole litre
pep_c Phosphoenolpyruvate
C3H2O6P
c 0.0 mmol 10 3 mole litre
pi_c Phosphate
HO4P
c 0.0 mmol 10 3 mole litre
pi_e Phosphate
HO4P
e 0.0 mmol 10 3 mole litre
pyr_c Pyruvate
C3H3O3
c 0.0 mmol 10 3 mole litre
pyr_e Pyruvate
C3H3O3
e 0.0 mmol 10 3 mole litre
q8_c Ubiquinone-8
C49H74O4
c 0.0 mmol 10 3 mole litre
q8h2_c Ubiquinol-8
C49H76O4
c 0.0 mmol 10 3 mole litre
r5p_c Alpha-D-Ribose 5-phosphate
C5H9O8P
c 0.0 mmol 10 3 mole litre
ru5p__D_c D-Ribulose 5-phosphate
C5H9O8P
c 0.0 mmol 10 3 mole litre
s7p_c Sedoheptulose 7-phosphate
C7H13O10P
c 0.0 mmol 10 3 mole litre
succ_c Succinate
C4H4O4
c 0.0 mmol 10 3 mole litre
succ_e Succinate
C4H4O4
e 0.0 mmol 10 3 mole litre
succoa_c Succinyl-CoA
C25H35N7O19P3S
c 0.0 mmol 10 3 mole litre
xu5p__D_c D-Xylulose 5-phosphate
C5H9O8P
c 0.0 mmol 10 3 mole litre

Parameters [45] name value unit derived unit constant sbo cvterm
cobra_default_lb cobra default - lb -1000.0 mmol_per_gDW_per_hr 10 3 mole g 3600 s
cobra_default_ub cobra default - ub 1000.0 mmol_per_gDW_per_hr 10 3 mole g 3600 s
cobra_0_bound cobra 0 - bound 0.0 mmol_per_gDW_per_hr 10 3 mole g 3600 s
R_ATPM_lower_bound R ATPM lower - bound 0.0 mmol_per_gDW_per_hr 10 3 mole g 3600 s
R_EX_glc__D_e_lower_bound R EX glc-D e lower - bound -10.0 mmol_per_gDW_per_hr 10 3 mole g 3600 s
lb_EX_pi_e -1000.0 mmol_per_h 10 3 mole 3600 s
ub_EX_pi_e 1000.0 mmol_per_h 10 3 mole 3600 s
lb_EX_for_e 0.0 mmol_per_h 10 3 mole 3600 s
ub_EX_for_e 1000.0 mmol_per_h 10 3 mole 3600 s
lb_EX_h_e -1000.0 mmol_per_h 10 3 mole 3600 s
ub_EX_h_e 1000.0 mmol_per_h 10 3 mole 3600 s
lb_EX_o2_e -1000.0 mmol_per_h 10 3 mole 3600 s
ub_EX_o2_e 1000.0 mmol_per_h 10 3 mole 3600 s
lb_EX_lac__D_e 0.0 mmol_per_h 10 3 mole 3600 s
ub_EX_lac__D_e 1000.0 mmol_per_h 10 3 mole 3600 s
lb_EX_pyr_e 0.0 mmol_per_h 10 3 mole 3600 s
ub_EX_pyr_e 1000.0 mmol_per_h 10 3 mole 3600 s
lb_EX_etoh_e 0.0 mmol_per_h 10 3 mole 3600 s
ub_EX_etoh_e 1000.0 mmol_per_h 10 3 mole 3600 s
lb_EX_gln__L_e 0.0 mmol_per_h 10 3 mole 3600 s
ub_EX_gln__L_e 1000.0 mmol_per_h 10 3 mole 3600 s
lb_EX_akg_e 0.0 mmol_per_h 10 3 mole 3600 s
ub_EX_akg_e 1000.0 mmol_per_h 10 3 mole 3600 s
lb_EX_co2_e -1000.0 mmol_per_h 10 3 mole 3600 s
ub_EX_co2_e 1000.0 mmol_per_h 10 3 mole 3600 s
lb_EX_acald_e 0.0 mmol_per_h 10 3 mole 3600 s
ub_EX_acald_e 1000.0 mmol_per_h 10 3 mole 3600 s
lb_EX_glu__L_e 0.0 mmol_per_h 10 3 mole 3600 s
ub_EX_glu__L_e 1000.0 mmol_per_h 10 3 mole 3600 s
lb_EX_mal__L_e 0.0 mmol_per_h 10 3 mole 3600 s
ub_EX_mal__L_e 1000.0 mmol_per_h 10 3 mole 3600 s
lb_EX_fum_e 0.0 mmol_per_h 10 3 mole 3600 s
ub_EX_fum_e 1000.0 mmol_per_h 10 3 mole 3600 s
lb_EX_fru_e 0.0 mmol_per_h 10 3 mole 3600 s
ub_EX_fru_e 1000.0 mmol_per_h 10 3 mole 3600 s
lb_EX_succ_e 0.0 mmol_per_h 10 3 mole 3600 s
ub_EX_succ_e 1000.0 mmol_per_h 10 3 mole 3600 s
lb_EX_h2o_e -1000.0 mmol_per_h 10 3 mole 3600 s
ub_EX_h2o_e 1000.0 mmol_per_h 10 3 mole 3600 s
lb_EX_nh4_e -1000.0 mmol_per_h 10 3 mole 3600 s
ub_EX_nh4_e 1000.0 mmol_per_h 10 3 mole 3600 s
lb_EX_ac_e 0.0 mmol_per_h 10 3 mole 3600 s
ub_EX_ac_e 1000.0 mmol_per_h 10 3 mole 3600 s
lb_EX_glc__D_e -10.0 mmol_per_h 10 3 mole 3600 s
ub_EX_glc__D_e 1000.0 mmol_per_h 10 3 mole 3600 s

Reactions [95] name equation modifiers formula derived units sbo cvterm
ACALD Acetaldehyde dehydrogenase (acetylating) acald_c + coa_c + nad_c ⇆ accoa_c + h_c + nadh_c
BQB_IS
ACALD
ACALDt Acetaldehyde reversible transport acald_e ⇆ acald_c
BQB_IS
ACALDt
ACKr Acetate kinase ac_c + atp_c ⇆ actp_c + adp_c
BQB_IS
ACKr
ACONTa Aconitase (half-reaction A, Citrate hydro-lyase) cit_c ⇆ acon_C_c + h2o_c
BQB_IS
ACONTa
ACONTb Aconitase (half-reaction B, Isocitrate hydro-lyase) acon_C_c + h2o_c ⇆ icit_c
BQB_IS
ACONTb
ACt2r Acetate reversible transport via proton symport ac_e + h_e ⇆ ac_c + h_c
BQB_IS
ACt2r
ADK1 Adenylate kinase amp_c + atp_c ⇆ 2.0 adp_c
BQB_IS
ADK1
AKGDH 2-Oxogluterate dehydrogenase akg_c + coa_c + nad_c ➞ co2_c + nadh_c + succoa_c
BQB_IS
AKGDH
AKGt2r 2 oxoglutarate reversible transport via symport akg_e + h_e ⇆ akg_c + h_c
BQB_IS
AKGt2r
ALCD2x Alcohol dehydrogenase (ethanol) etoh_c + nad_c ⇆ acald_c + h_c + nadh_c
BQB_IS
ALCD2x
ATPM ATP maintenance requirement atp_c + h2o_c ➞ adp_c + h_c + pi_c
BQB_IS
ATPM
ATPS4r ATP synthase (four protons for one ATP) adp_c + 4.0 h_e + pi_c ⇆ atp_c + h2o_c + 3.0 h_c
BQB_IS
ATPS4r
BIOMASS_Ecoli_core_w_GAM Biomass Objective Function with GAM 1.496 M_3pg_c + 3.7478 accoa_c + 59.81 atp_c + 0.361 e4p_c + 0.0709 f6p_c + 0.129 g3p_c + 0.205 g6p_c + 0.2557 gln__L_c + 4.9414 glu__L_c + 59.81 h2o_c + 3.547 nad_c + 13.0279 nadph_c + 1.7867 oaa_c + 0.5191 pep_c + 2.8328 pyr_c + 0.8977 r5p_c ➞ 59.81 adp_c + 4.1182 akg_c + 3.7478 coa_c + 59.81 h_c + 3.547 nadh_c + 13.0279 nadp_c + 59.81 pi_c
CO2t CO2 transporter via diffusion co2_e ⇆ co2_c
BQB_IS
CO2t
CS Citrate synthase accoa_c + h2o_c + oaa_c ➞ cit_c + coa_c + h_c
BQB_IS
CS
CYTBD Cytochrome oxidase bd (ubiquinol-8: 2 protons) 2.0 h_c + 0.5 o2_c + q8h2_c ➞ h2o_c + 2.0 h_e + q8_c
BQB_IS
CYTBD
D_LACt2 D lactate transport via proton symport h_e + lac__D_e ⇆ h_c + lac__D_c
BQB_IS
D_LACt2
ENO Enolase M_2pg_c ⇆ h2o_c + pep_c
BQB_IS
ENO
ETOHt2r ETOHt2r etoh_e + h_e ⇆ etoh_c + h_c
BQB_IS
ETOHt2r
EX_ac_e Acetate exchange ac_e ➞
BQB_IS
ac
EX_acald_e Acetaldehyde exchange acald_e ➞
BQB_IS
acald
EX_akg_e 2-Oxoglutarate exchange akg_e ➞
BQB_IS
akg
EX_co2_e CO2 exchange co2_e ⇆
BQB_IS
co2
EX_etoh_e Ethanol exchange etoh_e ➞
BQB_IS
etoh
EX_for_e Formate exchange for_e ➞
BQB_IS
for
EX_fru_e D-Fructose exchange fru_e ➞
BQB_IS
fru
EX_fum_e Fumarate exchange fum_e ➞
BQB_IS
fum
EX_glc__D_e D-Glucose exchange glc__D_e ⇆
BQB_IS
glc__D
EX_gln__L_e L-Glutamine exchange gln__L_e ➞
BQB_IS
gln__L
EX_glu__L_e L-Glutamate exchange glu__L_e ➞
BQB_IS
glu__L
EX_h_e H+ exchange h_e ⇆
BQB_IS
h
EX_h2o_e H2O exchange h2o_e ⇆
BQB_IS
h2o
EX_lac__D_e D-lactate exchange lac__D_e ➞
BQB_IS
lac__D
EX_mal__L_e L-Malate exchange mal__L_e ➞
BQB_IS
mal__L
EX_nh4_e Ammonia exchange nh4_e ⇆
BQB_IS
nh4
EX_o2_e O2 exchange o2_e ⇆
BQB_IS
o2
EX_pi_e Phosphate exchange pi_e ⇆
BQB_IS
pi
EX_pyr_e Pyruvate exchange pyr_e ➞
BQB_IS
pyr
EX_succ_e Succinate exchange succ_e ➞
BQB_IS
succ
FBA Fructose-bisphosphate aldolase fdp_c ⇆ dhap_c + g3p_c
BQB_IS
FBA
FBP Fructose-bisphosphatase fdp_c + h2o_c ➞ f6p_c + pi_c
BQB_IS
FBP
FORt2 Formate transport in via proton symport for_e + h_e ➞ for_c + h_c
BQB_IS
FORt2
FORti Formate transport via diffusion for_c ➞ for_e
BQB_IS
FORti
FRD7 Fumarate reductase fum_c + q8h2_c ➞ q8_c + succ_c
BQB_IS
FRD7
FRUpts2 Fructose transport via PEP:Pyr PTS (f6p generating) fru_e + pep_c ➞ f6p_c + pyr_c
BQB_IS
FRUpts2
FUM Fumarase fum_c + h2o_c ⇆ mal__L_c
BQB_IS
FUM
FUMt2_2 Fumarate transport via proton symport (2 H) fum_e + 2.0 h_e ➞ fum_c + 2.0 h_c
BQB_IS
FUMt2_2
G6PDH2r Glucose 6-phosphate dehydrogenase g6p_c + nadp_c ⇆ M_6pgl_c + h_c + nadph_c
BQB_IS
G6PDH2r
GAPD Glyceraldehyde-3-phosphate dehydrogenase g3p_c + nad_c + pi_c ⇆ M_13dpg_c + h_c + nadh_c
BQB_IS
GAPD
GLCpts D-glucose transport via PEP:Pyr PTS glc__D_e + pep_c ➞ g6p_c + pyr_c
BQB_IS
GLCpts
GLNS Glutamine synthetase atp_c + glu__L_c + nh4_c ➞ adp_c + gln__L_c + h_c + pi_c
BQB_IS
GLNS
GLNabc GLNabc atp_c + gln__L_e + h2o_c ➞ adp_c + gln__L_c + h_c + pi_c
BQB_IS
GLNabc
GLUDy Glutamate dehydrogenase (NADP) glu__L_c + h2o_c + nadp_c ⇆ akg_c + h_c + nadph_c + nh4_c
BQB_IS
GLUDy
GLUN Glutaminase gln__L_c + h2o_c ➞ glu__L_c + nh4_c
BQB_IS
GLUN
GLUSy Glutamate synthase (NADPH) akg_c + gln__L_c + h_c + nadph_c ➞ 2.0 glu__L_c + nadp_c
BQB_IS
GLUSy
GLUt2r L glutamate transport via proton symport reversible glu__L_e + h_e ⇆ glu__L_c + h_c
BQB_IS
GLUt2r
GND Phosphogluconate dehydrogenase M_6pgc_c + nadp_c ➞ co2_c + nadph_c + ru5p__D_c
BQB_IS
GND
H2Ot H2O transport via diffusion h2o_e ⇆ h2o_c
BQB_IS
H2Ot
ICDHyr Isocitrate dehydrogenase (NADP) icit_c + nadp_c ⇆ akg_c + co2_c + nadph_c
BQB_IS
ICDHyr
ICL Isocitrate lyase icit_c ➞ glx_c + succ_c
BQB_IS
ICL
LDH_D D-lactate dehydrogenase lac__D_c + nad_c ⇆ h_c + nadh_c + pyr_c
BQB_IS
LDH_D
MALS Malate synthase accoa_c + glx_c + h2o_c ➞ coa_c + h_c + mal__L_c
BQB_IS
MALS
MALt2_2 Malate transport via proton symport (2 H) 2.0 h_e + mal__L_e ➞ 2.0 h_c + mal__L_c
BQB_IS
MALt2_2
MDH Malate dehydrogenase mal__L_c + nad_c ⇆ h_c + nadh_c + oaa_c
BQB_IS
MDH
ME1 Malic enzyme (NAD) mal__L_c + nad_c ➞ co2_c + nadh_c + pyr_c
BQB_IS
ME1
ME2 Malic enzyme (NADP) mal__L_c + nadp_c ➞ co2_c + nadph_c + pyr_c
BQB_IS
ME2
NADH16 NADH dehydrogenase (ubiquinone-8 & 3 protons) 4.0 h_c + nadh_c + q8_c ➞ 3.0 h_e + nad_c + q8h2_c
BQB_IS
NADH16
NADTRHD NAD transhydrogenase nad_c + nadph_c ➞ nadh_c + nadp_c
BQB_IS
NADTRHD
NH4t Ammonia reversible transport nh4_e ⇆ nh4_c
BQB_IS
NH4t
O2t O2 transport diffusion o2_e ⇆ o2_c
BQB_IS
O2t
PDH Pyruvate dehydrogenase coa_c + nad_c + pyr_c ➞ accoa_c + co2_c + nadh_c
BQB_IS
PDH
PFK Phosphofructokinase atp_c + f6p_c ➞ adp_c + fdp_c + h_c
BQB_IS
PFK
PFL Pyruvate formate lyase coa_c + pyr_c ➞ accoa_c + for_c
BQB_IS
PFL
PGI Glucose-6-phosphate isomerase g6p_c ⇆ f6p_c
BQB_IS
PGI
PGK Phosphoglycerate kinase M_3pg_c + atp_c ⇆ M_13dpg_c + adp_c
BQB_IS
PGK
PGL 6-phosphogluconolactonase M_6pgl_c + h2o_c ➞ M_6pgc_c + h_c
BQB_IS
PGL
PGM Phosphoglycerate mutase M_2pg_c ⇆ M_3pg_c
BQB_IS
PGM
PIt2r Phosphate reversible transport via symport h_e + pi_e ⇆ h_c + pi_c
BQB_IS
PIt2r
PPC Phosphoenolpyruvate carboxylase co2_c + h2o_c + pep_c ➞ h_c + oaa_c + pi_c
BQB_IS
PPC
PPCK Phosphoenolpyruvate carboxykinase atp_c + oaa_c ➞ adp_c + co2_c + pep_c
BQB_IS
PPCK
PPS Phosphoenolpyruvate synthase atp_c + h2o_c + pyr_c ➞ amp_c + 2.0 h_c + pep_c + pi_c
BQB_IS
PPS
PTAr Phosphotransacetylase accoa_c + pi_c ⇆ actp_c + coa_c
BQB_IS
PTAr
PYK Pyruvate kinase adp_c + h_c + pep_c ➞ atp_c + pyr_c
BQB_IS
PYK
PYRt2 Pyruvate transport in via proton symport h_e + pyr_e ⇆ h_c + pyr_c
BQB_IS
PYRt2
RPE Ribulose 5-phosphate 3-epimerase ru5p__D_c ⇆ xu5p__D_c
BQB_IS
RPE
RPI Ribose-5-phosphate isomerase r5p_c ⇆ ru5p__D_c
BQB_IS
RPI
SUCCt2_2 Succinate transport via proton symport (2 H) 2.0 h_e + succ_e ➞ 2.0 h_c + succ_c
BQB_IS
SUCCt2_2
SUCCt3 Succinate transport out via proton antiport h_e + succ_c ➞ h_c + succ_e
BQB_IS
SUCCt3
SUCDi Succinate dehydrogenase (irreversible) q8_c + succ_c ➞ fum_c + q8h2_c
BQB_IS
SUCDi
SUCOAS Succinyl-CoA synthetase (ADP-forming) atp_c + coa_c + succ_c ⇆ adp_c + pi_c + succoa_c
BQB_IS
SUCOAS
TALA Transaldolase g3p_c + s7p_c ⇆ e4p_c + f6p_c
BQB_IS
TALA
THD2 NAD(P) transhydrogenase 2.0 h_e + nadh_c + nadp_c ➞ 2.0 h_c + nad_c + nadph_c
BQB_IS
THD2
TKT1 Transketolase r5p_c + xu5p__D_c ⇆ g3p_c + s7p_c
BQB_IS
TKT1
TKT2 Transketolase e4p_c + xu5p__D_c ⇆ f6p_c + g3p_c
BQB_IS
TKT2
TPI Triose-phosphate isomerase dhap_c ⇆ g3p_c
BQB_IS
TPI